Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow‐derived cells into the liver

Abstract

Transplanted BMC participate in the HGF-induced remodeling process of liver fibrosis. The roles of HGF in this process include the recruitment of BMC, possibly through increased expression of SDF-1 in part, as well as anti-apoptotic, mitogenic and antifibrotic activities on liver cells.