Mitochondria as the Primary Target of Resveratrol-Induced Apoptosis in Human Retinoblastoma Cells

Abstract

These results demonstrate that resveratrol, a nontoxic natural plant compound, inhibits Y79 cell proliferation and stimulates apoptosis through activation of the mitochondrial (intrinsic) apoptotic pathway and may warrant further exploration as an adjuvant to conventional anticancer therapies for retinoblastoma.