Distinct Caspase Cascades Are Initiated in Receptor-mediated and Chemical-induced Apoptosis

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.2K citations · Full text

Protein Function, Signal Transduction, Biochemistry +12

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

Apoptotic Program, Biochemistry, Medicine +11

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science · 1997 · 4.9K citations

Mitophagy, Apoptosis, Cell Death +17

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

Ruth M. Kluck, Ella Bossy‐Wetzel, Douglas R. Green et al. · Science · 1997 · 4.7K citations

Mitophagy, Apoptosis, Molecular Biology +19

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Damage +12