Concepedia

Asymmetric Synthesis of Quaternary α-Amino Phosphonates Using Sulfinimines

Franklin A. Davis, Seung Woong Lee, Hongxing Yan, Donald D. Titus

Organic Letters · 2001 · 79 citations · 31 references

DOI

Concepts

Abstract

The addition of lithium diethylphosphonate to enantiopure ketosulfinimines is highly diastereoselective (>95%), affording the first examples of quaternary alpha-alkyl alpha-amino (arylmethyl)phosphonates.

References

31

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Asymmetric Synthesis and Properties of Sulfinimines (Thiooxime <i>S</i>-Oxides)

Franklin A. Davis, Rajarathnam E. Reddy, Joanna M. Szewczyk et al. · The Journal of Organic Chemistry · 1997 · 199 citations

, , +9