Dipeptidyl nitriles as human dipeptidyl peptidase I inhibitors

L-<i>trans</i>-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

A. John Barrett, A A Kembhavi, M A Brown et al. · Biochemical Journal · 1982 · 1K citations · Full text

Glycobiology, Molecular Biology, Chemical Biology +19

1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(<i>S</i>)-pyrrolidine:  A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Edwin B. Villhauer, J. A. Brinkman, Goli B. Naderi et al. · Journal of Medicinal Chemistry · 2003 · 609 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B<i>in vivo</i>

Christine T. N. Pham, Timothy J. Ley · Proceedings of the National Academy of Sciences · 1999 · 392 citations

Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis

April M. Adkison, Sofia Z. Raptis, Diane G. Kelley et al. · Journal of Clinical Investigation · 2002 · 357 citations · Full text

Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis

April M. Adkison, Sofia Z. Raptis, Diane G. Kelley et al. · Journal of Clinical Investigation · 2002 · 341 citations

Immunology, Immune Regulation, Acute Experimental Arthritis +24