Chelerythrine Rapidly Induces Apoptosis through Generation of Reactive Oxygen Species in Cardiac Myocytes

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

Dominique Toullec, P. Pianetti, Hervé Coste et al. · Journal of Biological Chemistry · 1991 · 2.5K citations · Full text

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.

Roberta A. Gottlieb, Katharine O. Burleson, Robert A. Kloner et al. · Journal of Clinical Investigation · 1994 · 1.4K citations · Full text

Cardiac Muscle, Heart Failure, Apoptosis +18

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

Junichi Sadoshima, Seigo Izumo · Circulation Research · 1993 · 1.4K citations · Full text

Cardiac Muscle, Heart Failure, At1 Receptor Subtype +16

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

Quinn L. Deveraux · The EMBO Journal · 1998 · 1.4K citations · Full text

Signal Transduction, Apoptosis, Immunology +9

Chelerythrine is a potent and specific inhibitor of protein kinase C

Jean‐Marc Herbert, Jean‐Michel Augereau, J. Gleye et al. · Biochemical and Biophysical Research Communications · 1990 · 1.2K citations

Specific Inhibitor, Molecular Pharmacology, Signal Transduction +10