Concepedia

Measuring substrate binding and affinity of purified membrane transport proteins using the scintillation proximity assay

Daniel Harder, Dimitrios Fotiadis

Nature Protocols · 2012 · 65 citations · 28 references

DOI

Concepts

References

28

The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site

Lei Shi, Matthias Quick, Yongfang Zhao et al. · Molecular Cell · 2008 · 385 citations · Full text

, , +12

LeuT-Desipramine Structure Reveals How Antidepressants Block Neurotransmitter Reuptake

Zheng Zhou, Juan Zhen, Nathan K. Karpowich et al. · Science · 2007 · 335 citations · Full text

, , +17

Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures

Zheng Zhou, Juan Zhen, Nathan K. Karpowich et al. · Nature Structural & Molecular Biology · 2009 · 240 citations · Full text

, , +16

Scintillation proximity assay

Nigel Bosworth, Pat Towers · Nature · 1989 · 220 citations

Structure and mechanism of the uracil transporter UraA

Feiran Lu, Shuo Li, Yang Jiang et al. · Nature · 2011 · 214 citations

, , +5