PEGylated Hyaluronic Acid-Modified Liposomal Delivery System with Anti-γ-Glutamylcyclotransferase siRNA for Drug-Resistant MCF-7 Breast Cancer Therapy

PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles

Swaroop Mishra, Paul Webster, Mark E. Davis · European Journal of Cell Biology · 2004 · 725 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

Cancer related mutations in <i>NRF2</i> impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

Tatsuhiro Shibata, Tsutomu Ohta, Kit I. Tong et al. · Proceedings of the National Academy of Sciences · 2008 · 721 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

Tsutomu Ohta, Kumiko Iijima, Mamiko Miyamoto et al. · Cancer Research · 2008 · 628 citations

Medicine, Genetics, Oncology +15

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

Ping Zhang, Anju Singh, Srinivasan Yegnasubramanian et al. · Molecular Cancer Therapeutics · 2010 · 373 citations · Full text

Medicine, Molecular Biology, Oncology +17

Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels

Hyukjin Lee, Hyejung Mok, Yu‐Kyoung Oh et al. · Journal of Controlled Release · 2007 · 358 citations

Pharmacy, Biomedical Engineering, Pharmaceutics +14