Concepedia

Synthesis of 2-(aminomethyl)aziridines and their microwave-assisted ring opening to 1,2,3-triaminopropanes as novel antimalarial pharmacophores

Matthias D’hooghe, Sara Kenis, Karel Vervisch, Carmen Lategan, Peter J. Smith, Kelly Chibale, Norbert De Kimpe

European Journal of Medicinal Chemistry · 2010 · 36 citations · 36 references

DOIFull text

Open access

Concepts

References

36

Human Malaria Parasites in Continuous Culture

William Trager, James B. Jensen · Science · 1976 · 8K citations

, , +15

Receptors for Purines and Pyrimidines

Geoffrey Burnstock, Alexei Verkhratsky · 2012 · 4K citations

, , +10

Chiral Aziridines—Their Synthesis and Use in Stereoselective Transformations

David Tanner · Angewandte Chemie International Edition in English · 1994 · 1.1K citations

, , +10

Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines

Larry Rubinstein, Robert H. Shoemaker, Kenneth D. Paull et al. · JNCI Journal of the National Cancer Institute · 1990 · 931 citations

, , +14

Nucleophilic ring opening of aziridines

Xiaoyan Hu · Tetrahedron · 2004 · 881 citations

, , +5