A novel melittin-MhIL-2 fusion protein inhibits the growth of human ovarian cancer SKOV3 cells in vitro and in vivo tumor growth

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

Steven A. Rosenberg, Michael T. Lotze, Linda Muul et al. · New England Journal of Medicine · 1987 · 2.8K citations

Lymphoid Neoplasia, Advanced Cancer, Cancer Immunosurveillance +15

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

Doris A. Morgan, Francis W. Ruscetti, Robert C. Gallo · Science · 1976 · 2.5K citations

Cell Therapy, Conditioned Medium, Percent T Cells +15

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

Elizabeth A. Grimm, A Mazumder, H Z Zhang et al. · The Journal of Experimental Medicine · 1982 · 2.2K citations · Full text

Immunology, Immunologic Mechanism, Immune System +16

Interleukin-2 augments natural killer cell activity

Christopher S. Henney, Kagemasa Kuribayashi, D E Kern et al. · Nature · 1981 · 919 citations

Inflammation, Cytokine, Allergy +6

Durability of Complete Responses in Patients With Metastatic Cancer Treated With High-Dose Interleukin-2

Steven A. Rosenberg, James Chih‐Hsin Yang, Donald E. White et al. · Annals of Surgery · 1998 · 484 citations