A simple and efficient method for direct gene deletion in<i>Saccharomyces cerevisiae</i>

Alexis Baudin, Odile Ozier-Kalogéropoulos, Anne DENOUEL, +2

Nucleic Acids Research

Efficient MethodGeneticsMolecular BiologyMolecular GeneticsGenomics +14

Dichlorophenyl phosphoramidates as substrates for avian and mammalian liver phosphotriesterases: activity levels, calcium dependence and stereospecificity

Antonio Monroy‐Noyola, Miguel Á. Sogorb, N. Dı́az-Alejo, +4

Chemico-Biological Interactions

BiologyCalcium DependenceBiochemistryMammalian Liver PhosphotriesterasesMedicine +8

Contributions of polyol pathway to oxidative stress in diabetic cataract

Alan Yiu Wah Lee, STEPHEN S. M. CHUNG

The FASEB Journal

An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications

David K. Wilson, Kurt M. Bohren, Kenneth H. Gabbay, +1

Science

Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

Alan Yiu Wah Lee, Sookja Kim Chung, Stephen S.M. Chung

Proceedings of the National Academy of Sciences

Diabetic RetinopathyAr InhibitorsOcular DiseasePolyol AccumulationOphthalmology +11

Metabolism of the Lipid Peroxidation Product, 4-Hydroxy-trans-2-nonenal, in Isolated Perfused Rat Heart

Sanjay Srivastava, Animesh Chandra, Lifei Wang, +5

Journal of Biological Chemistry

Substrate specificity of human aldose reductase: identification of 4-hydroxynonenal as an endogenous substrate

David L. bander Jagt, Natasha S. Kolb, Timothy J. bander Jagt, +4

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Endogenous SubstrateBiosynthesisEngineeringAldo-keto ReductaseBiochemistry +10

Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Structure of the Y48H Mutant Enzyme

Kurt M. Bohren, Charles E. Grimshaw, Chung Jeng Lai, +4

Biochemistry

Three genes whose expression is induced by stress inSaccharomyces cerevisiae

Adriana Garay‐Arroyo, Alejandra A. Covarrubias

Yeast

Purification and partial characterization of an aldo-keto reductase from Saccharomyces cerevisiae

Annemarie Kuhn, C van Zyl, Alet van Tonder, +1

Applied and Environmental Microbiology

Aldehyde DehydrogenaseCellular EnzymologySaccharomyces CerevisiaeBiochemistryCytosolic Aldo-keto Reductase +10