Sookja Kim Chung

Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

Alan Yiu Wah Lee, Sookja Kim Chung, Stephen S.M. Chung · Proceedings of the National Academy of Sciences · 1995 · 310 citations

Life Sciences, Biochemistry, Genetics +15

Caveolin‐1 regulates nitric oxide‐mediated matrix metalloproteinases activity and blood–brain barrier permeability in focal cerebral ischemia and reperfusion injury

Yong Gu, Guo‐qing Zheng, Mingjing Xu et al. · Journal of Neurochemistry · 2011 · 257 citations

Life Sciences, Neurobiology, Neuroscience +17

Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of <i>db/db</i> Mice

Alvin K.H. Cheung, Maggie K.L. Fung, Terence T.L. Lam et al. · Diabetes · 2005 · 210 citations · Full text

Medicine, Endocrinology, Ophthalmology +17

Aldose Reductase–Deficient Mice Are Protected From Delayed Motor Nerve Conduction Velocity, Increased c-Jun NH2-Terminal Kinase Activation, Depletion of Reduced Glutathione, Increased Superoxide Accumulation, and DNA Damage

Eric C.M. Ho, Karen S.L. Lam, Yuk Shan Chen et al. · Diabetes · 2006 · 148 citations · Full text

Medicine, Biochemistry, Neuroscience +16

Fyn and p38 Signaling Are Both Required for Maximal Hypertonic Activation of the Osmotic Response Element-binding Protein/Tonicity-responsive Enhancer-binding Protein (OREBP/TonEBP)

Ben C.B. Ko, Amy K. M. Lam, András Kapùs et al. · Journal of Biological Chemistry · 2002 · 146 citations · Full text

Life Sciences, Molecular Biology, Physiology +17