Stephen S.M. Chung

Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.

Alan Yiu Wah Lee, Sookja Kim Chung, Stephen S.M. Chung · Proceedings of the National Academy of Sciences · 1995 · 310 citations

Life Sciences, Biochemistry, Genetics +15

Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of <i>db/db</i> Mice

Alvin K.H. Cheung, Maggie K.L. Fung, Terence T.L. Lam et al. · Diabetes · 2005 · 210 citations · Full text

Medicine, Endocrinology, Ophthalmology +17

Aldose Reductase–Deficient Mice Are Protected From Delayed Motor Nerve Conduction Velocity, Increased c-Jun NH2-Terminal Kinase Activation, Depletion of Reduced Glutathione, Increased Superoxide Accumulation, and DNA Damage

Eric C.M. Ho, Karen S.L. Lam, Yuk Shan Chen et al. · Diabetes · 2006 · 148 citations · Full text

Medicine, Biochemistry, Neuroscience +16

Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity <i>In vivo</i>

Vincent Kam Wai Wong, Pauline Chiu, Stephen S.M. Chung et al. · Clinical Cancer Research · 2005 · 109 citations

Medicine, Oncology, Pharmacology +17

Isoquercetin ameliorates hyperglycemia and regulates key enzymes of glucose metabolism via insulin signaling pathway in streptozotocin-induced diabetic rats

Muthukumaran Jayachandran, Tongze Zhang, Kumar Ganesan et al. · European Journal of Pharmacology · 2018 · 86 citations

Life Sciences, Biochemistry, Pharmacology +16