Changes in phosphorylation of ERK and Fos expression in dorsal horn neurons following noxious stimulation in a rat model of neuritis of the nerve root

Evidence for a central component of post-injury pain hypersensitivity

Clifford J. Woolf · Nature · 1983 · 2.1K citations

Nursing, Immunology, Neurology +14

Coupling of the RAS-MAPK Pathway to Gene Activation by RSK2, a Growth Factor-Regulated CREB Kinase

Jun Xing, David D. Ginty, Michael E. Greenberg · Science · 1996 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +17

Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

Li Chen, Li-Yen Mae Huang · Nature · 1992 · 965 citations

Medicine, Neurobiology, Neuroscience +14

Cross Talk between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation

Soren Impey, Karl Obrietan, Scott T. Wong et al. · Neuron · 1998 · 895 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

Ru‐Rong Ji, Hiroshi Baba, Gary J. Brenner et al. · Nature Neuroscience · 1999 · 784 citations

Life Sciences, Neurobiology, Neuroscience +14