Measurement of Drug Concentration in the Stomach After Intragastric Administration of Drug Solution to Healthy Volunteers: Analysis of Intragastric Fluid Dynamics and Drug Absorption

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging

Carsten Schiller, Carolin Fröhlich, Werner Siegmund et al. · Alimentary Pharmacology & Therapeutics · 2005 · 597 citations

Agriculture, Nutrition, Radiology +17

Simulation of fasting gastric conditions and its importance for the in vivo dissolution of lipophilic compounds

Maria Vertzoni, Jennifer Dressman, John M. Butler et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2005 · 355 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Gastric flow and mixing studied using computer simulation

Anupam Pal, K. Indireshkumar, Werner Schwizer et al. · Proceedings of the Royal Society B Biological Sciences · 2004 · 248 citations · Full text

Life Sciences, Physics, Physiology +17

A nonlinear least squares program based on differential equations, MULTI (RUNGE), for microcomputers.

Kiyoshi Yamaoka, Terumichi Nakagawa · Journal of Pharmacobio-Dynamics · 1983 · 191 citations · Full text

Natural Sciences, Computer Science, Mathematics +13