Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3

Alison C. MacKinnon, Michael Gibbons, Sarah L. Farnworth, Hakon Leffler, Ulf J. Nilsson, Tamara Delaine, A. John Simpson, Stuart J. Forbes, Nik Hirani, Jack Gauldie,

American Journal of Respiratory and Critical Care Medicine · 2011 · 508 citations · 41 references

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Abstract

This study identifies galectin-3 as an important regulator of lung fibrosis and provides a proof of principle for galectin-3 inhibition as a potential novel therapeutic strategy for IPF.

References

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