Concepedia

IgE Mediated Autoallergy against Thyroid Peroxidase – A Novel Pathomechanism of Chronic Spontaneous Urticaria?

Sabine Altrichter, H. Peter, Dina Pisarevskaja, Martin Metz, Peter Martus, Marcus Maurer

PLoS ONE · 2011 · 276 citations · 25 references

DOIFull text

Open access

Abstract

Our findings show that a sizeable subgroup of csU patients expresses IgE antibodies against thyroid peroxidase. These autoantibodies could cause "autoallergic" mast cell activation, a novel pathomechanism of chronic spontaneous urticaria.

References

25

EAACI/GA<sup>2</sup>LEN/EDF/WAO guideline: definition, classification and diagnosis of urticaria

Torsten Zuberbier, Riccardo Asero, Carsten Bindslev‐Jensen et al. · Allergy · 2009 · 706 citations

Identification of Profilin as a Novel Pollen Allergen; IgE Autoreactivity in Sensitized Individuals

Rudolf Valenta, Michael Duchêne, K. Pettenburger et al. · Science · 1991 · 642 citations

The autologous serum skin test: a screening test for autoantibodies in chronic idiopathic urticaria

SABROE, Grattan, Francis et al. · British Journal of Dermatology · 1999 · 422 citations

Detection of circulating histamine releasing autoantibodies with functional properties of anti‐IgE in chronic urticaria

Clive Grattan, David M. Francis, Michihiro Hide et al. · Clinical & Experimental Allergy · 1991 · 331 citations

Serum IgG autoantibodies directed against the alpha chain of Fc epsilon RI: a selective marker and pathogenetic factor for a distinct subset of chronic urticaria patients?

Edda Fiebiger, Dieter Maurer, Henriette Holub et al. · Journal of Clinical Investigation · 1995 · 295 citations · Full text

, , +23