Archives of Ophthalmology · 1951 · 24 citations · 4 references
Microbial PathogensImmunologyRoutine Culturing ProceduresAnterior ChamberDermatologyInflammationAerobic CulturingHealth SciencesBacterial InfectionsHumoral ImmunityImmune FunctionAqueous HumourClinical MicrobiologyPhagocyteMicrobial DiseaseAntibioticsPathogenesisAqueous HumorMicrobiologyMedicine
IN THE last ten years, Amsler, Verrey, and co-workers<sup>1</sup>have reported repeatedly on the cytology, bacteriology, and chemistry of the aqueous humor of patients with uveitis. By means of improved methods of puncturing the anterior chamber and of augmenting the yield of cellular material in the withdrawn samples of aqueous humor by centrifugation, these investigators have been able to revise the conclusions drawn from earlier studies<sup>2</sup>of a similar nature which had been carried out on a much smaller scale. One of their results has great practical implications, i. e., the finding of a relatively high incidence of phagocytosis of both bacilli and cocci by cells in the anterior chambers of patients with uveitis, an observation in striking contrast to the only rarely positive results achieved by routine culturing procedures. This observation, if confirmed, would modify dramatically the present concept of the pathogenesis of many inflammatory processes involving
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