Concepedia

Reversed CD4/CD8 ratios of tumor-infiltrating lymphocytes are correlated with the progression of human cervical carcinoma

Bor‐Ching Sheu, Su-Ming Hsu, Hong‐Nerng Ho, Rong‐Hwa Lin, Pao‐Ling Torng, Su-Cheng Huang

Cancer · 1999 · 107 citations · 24 references

DOIFull text

Open access

Abstract

Decreased proportions of tumor-infiltrating CD4+ T cells with reversed CD4/CD8 ratios are highly correlated with rapid tumor growth and lymph node metastasis in cervical carcinoma. The regional immune escape is of prognostic importance with regard to cancer progression.

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