Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis

Anti-Angiogenesis

Judah Folkman · Annals of Surgery · 1972 · 1.2K citations · Full text

Medicine, Pediatrics, Surgery +2

Cathepsin D protease mediates programmed cell death induced by interferon‐gamma, Fas/APO‐1 and TNF‐alpha.

Louis P. Deiss, H. Galinka, Hanna Berissi et al. · The EMBO Journal · 1996 · 462 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells.

Paul Säftig, Michal Hetman, Wolfgang W. Schmahl et al. · The EMBO Journal · 1995 · 442 citations · Full text

Medicine, Pathobiology, Pathology +17

The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress

Katarina Kågedal, Uno Johansson, Karin Öllinger · The FASEB Journal · 2001 · 282 citations

Life Sciences, Biochemistry, Cell Biology +15

Autocrine Growth Stimulation of the MCF 7 Breast Cancer Cells by the Estrogen-Regulated 52 K Protein*

FRANCHISE VIGNON, FRANQOISE CAPONY, MONIQUE GHAMBON et al. · Endocrinology · 1986 · 273 citations

Life Sciences, Biochemistry, Endocrinology +13