Peroxisome proliferator-activated receptors γ and α agonists stimulate cardiac glucose uptake via activation of AMP-activated protein kinase

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

Life Sciences, Cell Biology, Molecular Biology +12

A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle

James Mu, Joseph T. Brozinick, Otto Valladares et al. · Molecular Cell · 2001 · 924 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise

W. W. Winder, D. Grahame Hardie · American Journal of Physiology-Endocrinology and Metabolism · 1996 · 795 citations

Life Sciences, Biochemistry, Physiology +17

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

Raymond R. Russell, Ji Li, David Coven et al. · Journal of Clinical Investigation · 2004 · 723 citations · Full text

Life Sciences, Cardiology, Physiology +16

High Rates of Fatty Acid Oxidation during Reperfusion of Ischemic Hearts Are Associated with a Decrease in Malonyl-CoA Levels Due to an Increase in 5’-AMP-activated Protein Kinase Inhibition of Acetyl-CoA Carboxylase

Naomi Kudo, Amy Barr, Rick L. Barr et al. · Journal of Biological Chemistry · 1995 · 577 citations · Full text

Life Sciences, Biochemistry, Physiology +17