Concepedia

Disruption of ShcA signaling halts cell proliferation — characterization of ShcC residues that influence signaling pathways using yeast

Julia Heinrich, Seung Kwak, David Howland, Jin Chen, Stephen Sturner, Kelly D. Sullivan, Kerri Lipinski, Ke-Yi Cheng, Yijin She, Frederick Lo

Cellular Signalling · 2005 · 15 citations · 25 references

DOI

Concepts

References

25

The p66shc adaptor protein controls oxidative stress response and life span in mammals

Enrica Migliaccio, Marco Giorgio, Simonetta Mele et al. · Nature · 1999 · 1.7K citations

, , +16

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Giuliana Pelicci, Luisa Lanfrancone, F Grignani et al. · Cell · 1992 · 1.3K citations

, , +14

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Sean E. Egan, B.W. Giddings, Mary W. Brooks et al. · Nature · 1993 · 1.2K citations

, , +14

Stable suppression of gene expression by RNAi in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Gregory J. Hannon · Proceedings of the National Academy of Sciences · 2002 · 550 citations · Full text

, , +9

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway

Ami Aronheim, David Engelberg, Nanxin Li et al. · Cell · 1994 · 459 citations

, , +12