Publication | Open Access

Germline PTEN Promoter Mutations and Deletions in Cowden/Bannayan-Riley-Ruvalcaba Syndrome Result in Aberrant PTEN Protein and Dysregulation of the Phosphoinositol-3-Kinase/Akt Pathway

Signal TransductionReceptor Tyrosine KinaseGeneticsPathogenesisPhosphoinositol-3-kinase/akt PathwayPathologyAberrant Pten ProteinGene ExpressionMedicineCell SignalingCowden/bannayan-riley-ruvalcaba Syndrome Result