Decoupling of Tumor-Initiating Activity from Stable Immunophenotype in HoxA9-Meis1-Driven AML

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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Identification and expansion of human colon-cancer-initiating cells

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Medicine, Cancer Biology, Oncology +12

Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells

Michael F. Clarke, John E. Dick, Peter B. Dirks et al. · Cancer Research · 2006 · 3.1K citations

Medicine, Cancer Biology, Oncology +17

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

Sean C. Bendall, Erin F. Simonds, Peng Qiu et al. · Science · 2011 · 2.4K citations

Life Sciences, Cell Biology, Immunology +11

<i>DNMT3A</i> Mutations in Acute Myeloid Leukemia

Timothy J. Ley, Li Ding, Matthew J. Walter et al. · New England Journal of Medicine · 2010 · 2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17