Identification of a High-Affinity Ligand That Exhibits Complete Aryl Hydrocarbon Receptor Antagonism

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

Francisco J. Quintana, Alexandre S. Basso, Antonio Iglesias et al. · Nature · 2008 · 1.8K citations

Signal Transduction, Molecular Physiology, Molecular Regulation +9

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

Marc Veldhoen, Keiji Hirota, Astrid M. Westendorf et al. · Nature · 2008 · 1.6K citations

Inflammation, Autoimmune Disease, Immunotoxicology +8

Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells

Anthony E. Boitano, Jian Wang, Russell D. Romeo et al. · Science · 2010 · 1K citations · Full text

Ex Vivo Expansion, Cell Therapy, Immunology +17

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

Akihiro Kimura, Tetsuji Naka, Keiko Nohara et al. · Proceedings of the National Academy of Sciences · 2008 · 512 citations · Full text

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

Marc Veldhoen, Keiji Hirota, Jillian R. Christensen et al. · The Journal of Experimental Medicine · 2008 · 509 citations · Full text