Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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Energy Metabolism, Signal Transduction, Biochemistry +14

Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1

Joseph T. Rodgers, Carles Lerín, Wilhelm Haas et al. · Nature · 2005 · 3.1K citations

Energy Homeostasis, Nutrient Signalling, Physiology +7

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jäger, Christoph Handschin, Julie St‐Pierre et al. · Proceedings of the National Academy of Sciences · 2007 · 2.4K citations · Full text

Muscle Function, Direct Phosphorylation, Metabolic Remodeling +21

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki et al. · Nature · 2006 · 2.1K citations · Full text

Metabolic Syndrome, Nutrition, Energy Metabolism +12