Concepedia

Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists

Alessandra Ammazzalorso, Antonella Giancristofaro, Alessandra D’Angelo, Barbara De Filippis, Marialuigia Fantacuzzi, Letizia Giampietro, Cristina Maccallini, Rosa Amoroso

Bioorganic & Medicinal Chemistry Letters · 2011 · 42 citations · 12 references

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12

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

Isabelle Issemann, Stephen Green · Nature · 1990 · 3.5K citations

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1997 · 2.2K citations · Full text

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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα

H. Eric Xu, Thomas B. Stanley, Valerie G. Montana et al. · Nature · 2002 · 611 citations

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Differential Gene Regulation in Human Versus Rodent Hepatocytes by Peroxisome Proliferator-activated Receptor (PPAR) α

Jeffrey Lawrence, Ying Li, Shiying Chen et al. · Journal of Biological Chemistry · 2001 · 192 citations · Full text

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Identification of a subtype selective human PPARα agonist through parallel-array synthesis

Peter J. Brown, L. William Stuart, Kevin P. Hurley et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 178 citations · Full text

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