Synthesis, biological evaluation, and docking study of indole aryl sulfonamides as aromatase inhibitors

Marialuigia Fantacuzzi, Barbara De Filippis, Marialucia Gallorini, +9

European Journal of Medicinal Chemistry

Inhibitory ActivityMedicinal ChemistryBiochemistryMedicineNatural Sciences +8

Design, synthesis and biological evaluation of imidazole and triazole-based carbamates as novel aromatase inhibitors

Alessandra Ammazzalorso, Marialucia Gallorini, Marialuigia Fantacuzzi, +7

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistryMedicineNatural Sciences +8

Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists

Alessandra Ammazzalorso, Antonella Giancristofaro, Alessandra D’Angelo, +5

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyPparα AntagonistsMedicinePharmacotherapyPharmacology +2

Novel aminobenzyl-acetamidine derivative modulate the differential regulation of NOSs in LPS induced inflammatory response: Role of PI3K/Akt pathway

Antonia Patruno, Sara Franceschelli, Mirko Pesce, +8

Biochimica et Biophysica Acta (BBA) - General Subjects

InflammationCytokineAnti-inflammatorySignal TransductionLung Inflammation +10

Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors

Mauro Di Matteo, Alessandra Ammazzalorso, Federico Andreoli, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryPiperidine SulfonamidesBiochemistryMedicineNatural Sciences +6

Structural development studies of PPARs ligands based on tyrosine scaffold

Barbara De Filippis, Pasquale Linciano, Alessandra Ammazzalorso, +9

European Journal of Medicinal Chemistry

Combinatorial ChemistryBiochemistryMedicineDrug DiscoveryNon-peptide Ligand +3

Synthesis and structure–activity relationships of fibrate-based analogues inside PPARs

Letizia Giampietro, Alessandra D’Angelo, Antonella Giancristofaro, +6

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicineFibrate-based AnaloguesChemical BiologyPharmacology +4

Synthesis, Biological Evaluation, and Docking Studies of N-Substituted Acetamidines as Selective Inhibitors of Inducible Nitric Oxide Synthase

Cristina Maccallini, Antonia Patruno, Neva Bešker, +11

Journal of Medicinal Chemistry

Selective InhibitorsPharmacotherapyChemical BiologyMedicinal ChemistryReactive Nitrogen Specie +14

Indazole, Pyrazole, and Oxazole Derivatives Targeting Nitric Oxide Synthases and Carbonic Anhydrases

Cristina Maccallini, Mauro Di Matteo, Daniela Vullo, +8

ChemMedChem

Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome

Letizia Giampietro, Antonio Laghezza, Carmen Cerchia, +16

ACS Medicinal Chemistry Letters

Molecular PharmacologyMetabolic SyndromeEnergy HomeostasisBiochemistryPpar Isoforms +13