Synthesis, antiviral, and anti-HIV-1 integrase activities of 3-aroyl-1,1-dioxo-1,4,2-benzodithiazines

Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

Daria J. Hazuda, Peter J. Felock, Marc Witmer et al. · Science · 2000 · 1.1K citations

Hiv-1 Integrase, Viral Replication, Immunology +19

New Soluble-Formazan Assay for HIV-1 Cytopathic Effects: Application to High-Flux Screening of Synthetic and Natural Products for AIDS-Antiviral Activity

O. S. Weislow, Rebecca Kiser, Donald L. Fine et al. · JNCI Journal of the National Cancer Institute · 1989 · 689 citations

Molecular Pharmacology, High-flux Screening, New Soluble-formazan Assay +13

Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors

Nouri Neamati, Abhijit Mazumder, Hong Zhao et al. · Antimicrobial Agents and Chemotherapy · 1997 · 103 citations · Full text

Immunology, Pharmacotherapy, Antiviral Drug +18

New Class of HIV Integrase Inhibitors that Block Viral Replication in Cell Culture

Christophe Pannecouque, Wim Pluymers, Bénédicte Van Maele et al. · Current Biology · 2002 · 100 citations · Full text

Antiviral Agents, Human Retrovirus, Pathogenesis +10

Application of CoMFA and CoMSIA 3D-QSAR and Docking Studies in Optimization of Mercaptobenzenesulfonamides as HIV-1 Integrase Inhibitors

Chih-Ling Kuo, Haregewein Assefa, Shantaram Kamath et al. · Journal of Medicinal Chemistry · 2003 · 80 citations · Full text

Molecular Biology, Chemistry, Antiviral Drug +16