Disease-Specific Induced Pluripotent Stem Cells

In-Hyun Park, Natasha Arora, Hongguang Huo, +7

Cell

Regenerative MedicineInduced Pluripotent Stem CellMedicineInduced Pluripotent Stem CellsStem Cell Research +4

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

Masanori Asakura, Masafumi Kitakaze, Seiji Takashima, +14

Nature Medicine

Adam12 ProcessingCardiac MuscleCardiomyopathyHeart FailureCardiovascular Disease +7

Abnormalities in human pluripotent cells due to reprogramming mechanisms

Hong Ma, Robert Morey, Ryan C. O’Neil, +23

Nature

Induced Pluripotent Stem CellDevelopmental BiologyCell SpecializationHuman Pluripotent CellsInduced Pluripotent Stem Cells +6

The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

Timothy D. O’Connell, Shinji Ishizaka, Akihiro Nakamura, +8

Journal of Clinical Investigation

The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse

Timothy D. O’Connell, Shinji Ishizaka, Akihiro Nakamura, +8

Journal of Clinical Investigation

Cardiac MuscleCardiac RegenerationDouble-knockout MouseCardiovascular FunctionCellular Physiology +20

α1-Adrenergic Receptor Subtype mRNAs Are Differentially Regulated by α1-Adrenergic and Other Hypertrophic Stimuli in Cardiac Myocytes in Culture and In Vivo

Gregg Rokosh, Alexandre F.R. Stewart, Kevin Chang, +5

Journal of Biological Chemistry

Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure

Mihaela Gherghiceanu, Lili Barad, Atara Novak, +4

Journal of Cellular and Molecular Medicine

Cardiac MuscleAdult Stem CellCardiac Progenitor CellsUltrastructural FeaturesCellular Physiology +17

Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?

Gábor Földes, Maxime Mioulane, Jamie Wright, +7

Journal of Molecular and Cellular Cardiology

Network Reconstruction and Systems Analysis of Cardiac Myocyte Hypertrophy Signaling

Karen A. Ryall, David O. Holland, Kyle A. Delaney, +3

Journal of Biological Chemistry

MechanobiologyCardiac MuscleCardiomyopathySignal TransductionEngineering +11

Phenotypic Screening with Human iPS Cell–Derived Cardiomyocytes: HTS-Compatible Assays for Interrogating Cardiac Hypertrophy

Coby B. Carlson, Chad H. Koonce, Natsuyo Aoyama, +6

SLAS DISCOVERY

Cardiac MuscleHeart FailureEngineeringCardiac Progenitor CellsBiomedical Engineering +16