Activation of Toll-like receptor-3 induces interferon-λ expression in human neuronal cells

IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex

Sergei V. Kotenko, Grant Gallagher, Vitaliy V. Baurin et al. · Nature Immunology · 2002 · 1.8K citations

Immunology, Antiviral Drug Development, Antiviral Response +5

IL-28, IL-29 and their class II cytokine receptor IL-28R

Paul O. Sheppard, Wayne Kindsvogel, Wenfeng Xu et al. · Nature Immunology · 2002 · 1.6K citations

Inflammation, Cytokine, Immune Regulation +2

Vpr Is Required for Efficient Replication of Human Immunodeficiency Virus Type-1 in Mononuclear Phagocytes

Ruth I. Connor, Benjamin K. Chen, Sunny Choe et al. · Virology · 1995 · 1.3K citations · Full text

Viral Replication, 96-Amino Acid, Immunology +16

Microglia Initiate Central Nervous System Innate and Adaptive Immune Responses through Multiple TLRs

Julie K. Olson, Stephen D. Miller · The Journal of Immunology · 2004 · 1.2K citations · Full text

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

Seija Lehnardt, Leon J. Massillon, Pamela L. Follett et al. · Proceedings of the National Academy of Sciences · 2003 · 1K citations · Full text

Inflammation, Toll-like Receptors, Neurodegenerative Diseases +15