Seija Lehnardt

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

Seija Lehnardt, Leon J. Massillon, Pamela L. Follett et al. · Proceedings of the National Academy of Sciences · 2003 · 1K citations · Full text

Inflammation, Toll-like Receptors, Neurodegenerative Diseases +15

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

Sabrina Lehmann, Christina Krüger, Boyoun Park et al. · Nature Neuroscience · 2012 · 758 citations

Inflammation, Toll-like Receptors, Medicine +10

The Toll-Like Receptor TLR4 Is Necessary for Lipopolysaccharide-Induced Oligodendrocyte Injury in the CNS

Seija Lehnardt, Christian Lachance, Silvia Patrizi et al. · Journal of Neuroscience · 2002 · 676 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +17

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

D. Marković, Katyayni Vinnakota, Sridhar Reddy Chirasani et al. · Proceedings of the National Academy of Sciences · 2009 · 382 citations · Full text

Neuro-oncology, Glioma, Medicine +15

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

Volker Siffrin, Helena Radbruch, Robert Glumm et al. · Immunity · 2010 · 316 citations · Full text

Vivo Imaging, Neurological Disorder, Medicine +9