Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: An in vivo autoradiographic study

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

J. William Langston, Philip L. Ballard, James W. Tetrud et al. · Science · 1983 · 4.9K citations

Psychoactive Drug, Marked Parkinsonism, Medicine +15

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Neurotransmitter, Neurotransmission, Social Sciences +20

The projections of the ventral tegmental area and adjacent regions: A combined fluorescent retrograde tracer and immunofluorescence study in the rat

Larry W. Swanson · Brain Research Bulletin · 1982 · 1.7K citations

Neurophysiology, Neuroanatomy, Adjacent Regions +10

Efferent connections of the substantia nigra and ventral tegmental area in the rat

Robert M. Beckstead, Valerie B. Domesick, Walle J. H. Nauta · Brain Research · 1979 · 1.3K citations

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Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

Jonathan A. Javitch, Robert J. D’Amato, Stephen M. Strittmatter et al. · Proceedings of the National Academy of Sciences · 1985 · 1.3K citations · Full text

Parkinsonism-inducing Neurotoxin, Neurotransmitter, Dopamine Neurons +17