Concepedia

Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions

Altaf A. Dar, Alexander Zaika, M. Blanca Piazuelo, Pelayo Correa, Tatsuki Koyama, Abbes Belkhiri, Kay Washington, Antoni Castells, Manuel Pera, Wael El‐Rifai

Cancer · 2008 · 110 citations · 34 references

Open access

Abstract

Study results indicated that AURKA provides potent antiapoptotic properties to gastrointestinal cells by regulating levels of p53 through the AKT/HDM2 axis.

References

34

THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO‐CALLED INTESTINAL‐TYPE CARCINOMA

P Laurén · Acta Pathologica Microbiologica Scandinavica · 1965 · 6.1K citations

So‐called Intestinal‐type Carcinoma, Esophageal Cancer, Gastrointestinal Oncology +8

Cancer Statistics, 2006

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth M. Ward et al. · CA A Cancer Journal for Clinicians · 2006 · 5.3K citations · Full text

Epidemiology Of Cancer, Cancer Registration, Mortality Rates +17

Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

Tumor Biology, Tumor Suppressor, Medicine +3

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

Henryk Dudek, Sandeep Robert Datta, Thomas Franke et al. · Science · 1997 · 2.5K citations

Changing patterns in the incidence of esophageal and gastric carcinoma in the United States

Susan S. Devesa, William J. Blot, Joseph F. Fraumeni · Cancer · 1998 · 2.1K citations