Second-Hand Cigarette Smoke Impairs Bacterial Phagocytosis in Macrophages by Modulating CFTR Dependent Lipid-Rafts

Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms

Pradeep K. Singh, Amy L. Schaefer, Matthew R. Parsek et al. · Nature · 2000 · 1.5K citations

Medical Microbiology, Pathogenic Microbiology, Bacteriology +11

Chronic obstructive pulmonary disease: current burden and future projections

Alan D López, Kenji Shibuya, Chalapati Rao et al. · European Respiratory Journal · 2006 · 1.3K citations · Full text

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

Anke Di, Mary E. Brown, Ludmila V. Deriy et al. · Nature Cell Biology · 2006 · 476 citations

Macrophage Biology, Inflammation, Pathogenesis +7

Initiation of Biofilm Formation by <i>Pseudomonas aeruginosa</i> 57RP Correlates with Emergence of Hyperpiliated and Highly Adherent Phenotypic Variants Deficient in Swimming, Swarming, and Twitching Motilities

Éric Déziel, Yves Comeau, Richard Villemur · Journal of Bacteriology · 2001 · 446 citations · Full text

Biofilms, Pathogenic Microbiology, Biofilm Formation +15

Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells

Sandra Hodge, Greg Hodge, R Scicchitano et al. · Immunology and Cell Biology · 2003 · 431 citations