Preferential Repair of DNA Double-strand Break at the Active Gene in Vivo

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

R Sikorski, P. Hieter · Genetics · 1989 · 8.8K citations · Full text

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

Mark S. Longtine, Amos Mckenzie, Douglas J. DeMarini et al. · Yeast · 1998 · 5.5K citations

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

Frank C. P. Holstege, Ezra G. Jennings, John J. Wyrick et al. · Cell · 1998 · 1.7K citations · Full text

Functional Genomics, Regulatory Circuitry, Genetics +7

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

Vilhelm A. Bohr · Cell · 1985 · 1.2K citations

Chromatin, Genome Instability, Dna Damage +10

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

Isabel Mellon · Cell · 1987 · 1.2K citations

Chromatin, Genome Instability, Transcriptional Regulation +12