Isabel Mellon

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

Isabel Mellon · Cell · 1987 · 1.2K citations

Chromatin, Genome Instability, Transcriptional Regulation +12

Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

Isabel Mellon, Philip C. Hanawalt · Nature · 1989 · 578 citations

Genome Instability, Natural Sciences, Genetics +11

Preferential DNA repair of an active gene in human cells.

Isabel Mellon, Vilhelm A. Bohr, Charles A. Smith et al. · Proceedings of the National Academy of Sciences · 1986 · 448 citations

Dna Damage, Genetics, Molecular Biology +18

Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes

Isabel Mellon, Deepak K. Rajpal, Minoru Koi et al. · Science · 1996 · 287 citations

Genetics, Genomic Mechanism, Molecular Biology +16

Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli.

Isabel Mellon, Gregory N. Champe · Proceedings of the National Academy of Sciences · 1996 · 174 citations · Full text

Dna Damage, Genetics, Bacteriology +21