LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms

Timothy W. Lovenberg, Bruce M. Baron, Luı́s de Lecea et al. · Neuron · 1993 · 690 citations · Full text

Sleep, Alertness, Medicine +13

Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.

Jonathan Bard, J M Zgombick, Nika Adham et al. · Journal of Biological Chemistry · 1993 · 526 citations · Full text

Genetics, Neurotransmitter, Molecular Biology +16

A receptor autoradiographic and <i>in situ</i> hybridization analysis of the distribution of the 5‐ht₇ receptor in rat brain

Eric L. Gustafson, Margaret M. Durkin, Jonathan Bard et al. · British Journal of Pharmacology · 1996 · 291 citations · Full text

Characterization of SB‐269970‐A, a selective 5‐HT₇ receptor antagonist

Jim J. Hagan, Gary Price, Nigel Deeks et al. · British Journal of Pharmacology · 2000 · 281 citations · Full text

5-HT7 Receptor Inhibition and Inactivation Induce Antidepressantlike Behavior and Sleep Pattern

Peter B. Hedlund, Salvador Huitrón‐Reséndiz, Steven J. Henriksen et al. · Biological Psychiatry · 2005 · 271 citations

Sleep Disorders, Sleep, Sleep Disorder +14