The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

Robert F. Furchgott, John V. Zawadzki · Nature · 1980 · 12K citations

Life Sciences, Cell Biology, Physiology +15

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

Salvador Moncada, A.G. Herman, E.A. Higgs et al. · Thrombosis Research · 1977 · 684 citations

Medicine, Cell Biology, Pharmacology +14

Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery.

Jo G. R. De Mey, Marnix Claeys, PM Vanhoutte · Journal of Pharmacology and Experimental Therapeutics · 1982 · 348 citations

Medicine, Pharmacology, Physiology +13

Anoxia and endothelium‐dependent reactivity of the canine femoral artery.

Jo G. R. De Mey, Paul M. Vanhoutte · The Journal of Physiology · 1983 · 256 citations

Medicine, Pharmacology, Physiology +8

Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine

Johan Van de Voorde, I Leusen · European Journal of Pharmacology · 1983 · 251 citations

Life Sciences, Pharmacology, Physiology +9