Coordination of Rho Family GTPase Activities to Orchestrate Cytoskeleton Responses during Cell Wound Repair

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Catherine D. Nobes, Alan Hall · Cell · 1995 · 4.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

Masayoshi Uehata, Toshimasa Ishizaki, Hiroyuki Satoh et al. · Nature · 1997 · 2.9K citations

Life Sciences, Biochemistry, Cell Biology +16

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

Yuan Gao, J. Bradley Dickerson, Fukun Guo et al. · Proceedings of the National Academy of Sciences · 2004 · 1.1K citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Coordination of Rho GTPase activities during cell protrusion

Matthias Macháček, Louis Hodgson, Christopher M. Welch et al. · Nature · 2009 · 1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.

M Bubb, Adrian M. Senderowicz, Edward A. Sausville et al. · Journal of Biological Chemistry · 1994 · 818 citations · Full text

Life Sciences, Cell Biology, Pharmacology +15