PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension

Sequence Variations in <i>PCSK9,</i> Low LDL, and Protection against Coronary Heart Disease

Jonathan C. Cohen, Eric Boerwinkle, Thomas H. Mosley et al. · New England Journal of Medicine · 2006 · 3.2K citations · Full text

Medicine, Genetics, Molecular Genetics +17

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation

Nabil G. Seidah, Suzanne Benjannet, L. Alexandra Wickham et al. · Proceedings of the National Academy of Sciences · 2003 · 1.2K citations · Full text

Life Sciences, Biochemistry, Apoptosis +14

A 52-Week Placebo-Controlled Trial of Evolocumab in Hyperlipidemia

Dirk Blom, Tomas Hala, Michael A. Bolognese et al. · New England Journal of Medicine · 2014 · 713 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking <i>Pcsk9</i>

Shirya Rashid, David E. Curtis, Rita Garuti et al. · Proceedings of the National Academy of Sciences · 2005 · 677 citations

Life Sciences, Molecular Biology, Pharmacology +17

Molecular Characterization of Loss-of-Function Mutations in PCSK9 and Identification of a Compound Heterozygote

Zhenze Zhao, Yetsa Tuakli-Wosornu, Thomas A. Lagace et al. · The American Journal of Human Genetics · 2006 · 633 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13