The EMIT® FreeLevelTM Ultrafiltration Technique Compared with Equilibrium Dialysis and Ultracentrifugation to Determine Protein Binding of Phenytoin

Plasma protein binding of diphenylhydantoin in man; Interaction with other drugs and the effect of temperature and plasma dilution

M. Lunde Per Knut, Anders Rane, Summer J. Yaffe et al. · Clinical Pharmacology & Therapeutics · 1970 · 244 citations

Medicine, Pharmaceutics, Pharmacology +10

Serum Concentrations of Free Diphenylhydantoin and their Relationship To Clinical Intoxication

Harold E. Booker, Barbara A. Darcey · Epilepsia · 1973 · 142 citations

Medicine, Pharmacology, Toxicology +13

Importance of Protein Binding for the Interpretation of Serum or Plasma Drug Concentrations

David J. Greenblatt, Edward M. Sellers, Jan Koch‐Weser · The Journal of Clinical Pharmacology · 1982 · 136 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration.

Herbert Kurz, H. Trunk, B Weitz · PubMed · 1977 · 115 citations

Pharmacy, Biochemistry, Pharmacology +11

Plasma Protein Binding of Diphenylhydantoin in Man

P. K. M. Lunde · Acta Pharmacologica et Toxicologica · 1971 · 90 citations

Medicine, Pharmacology, Clinical Pharmacology +11