The CD4+CD25bright regulatory T cells and CTLA-4 expression in peripheral and decidual lymphocytes are down-regulated in human miscarriage

Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

Takeshi Takahashi, Tomoyuki Tagami, Sayuri Yamazaki et al. · The Journal of Experimental Medicine · 2000 · 2.2K citations · Full text

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Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

Simon Read, Vivianne Malmström, Fiona Powrie · The Journal of Experimental Medicine · 2000 · 2.2K citations

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Regulatory T cells mediate maternal tolerance to the fetus

Varuna Aluvihare, Marinos Kallikourdis, Alexander G. Betz · Nature Immunology · 2004 · 1.6K citations

Life Sciences, Immunology, Obstetrics +14

Normal human pregnancy is associated with an elevation in the immune suppressive CD25⁺ CD4⁺ regulatory T‐cell subset

David Somerset, Yong Zheng, Mark D. Kilby et al. · Immunology · 2004 · 752 citations · Full text

Life Sciences, Immunology, Obstetrics +17

Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases

Yasushi Sasaki · Molecular Human Reproduction · 2004 · 741 citations · Full text

Life Sciences, Cell Biology, Immunology +17