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PDK1 mediates growth factor‐induced Ral‐GEF activation by a kinase‐independent mechanism

Xuejun Tian, Gabriel Rusanescu, Weimin Hou, Brian Schaffhausen, Larry A. Feig

The EMBO Journal · 2002 · 71 citations · 40 references

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40

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

Dario R. Alessi, Stephen R. James, C. Peter Downes et al. · Current Biology · 1997 · 2.8K citations · Full text

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Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

David Stokoe, Terry Copeland, Piers R. J. Gaffney et al. · Science · 1997 · 1.2K citations

, , +15

Phosphorylation and Regulation of Raf by Akt (Protein Kinase B)

Sven Zimmermann, Karin Moelling · Science · 1999 · 1.1K citations

, , +17

Direct control of the Forkhead transcription factor AFX by protein kinase B

Geert J.P.L. Kops, Nancy D. de Ruiter, Alida M.M. de Vries-Smits et al. · Nature · 1999 · 1.1K citations

, , +10

The structural basis of the activation of Ras by Sos

P. Ann Boriack‐Sjodin, S.M. Margarit, Dafna Bar‐Sagi et al. · Nature · 1998 · 801 citations

, , +6