Concepedia

Protective effects of low and high doses of cyclosporin A against reoxygenation injury in isolated rat cardiomyocytes are associated with differential effects on mitochondrial calcium levels

Elinor J. Griffiths, Christopher Ocampo, Joshua Savage, Michael D. Stern, Howard S. Silverman

Cell Calcium · 2000 · 58 citations · 32 references

DOI

Concepts

References

32

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

, , +8

Myocardial calcium and magnesium in acute ischemic injury.

Anthony C. Shen, Robert B. Jennings · PubMed · 1972 · 631 citations

, , +10

Protection by Cyclosporin A of Ischemia/Reperfusion-Induced Damage in Isolated Rat Hearts

Elinor J. Griffiths, Andrew P. Halestrap · Journal of Molecular and Cellular Cardiology · 1993 · 574 citations

, , +14

Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

Andrew P. Halestrap, CP Connern, Elinor J. Griffiths et al. · 1997 · 420 citations

, , +17

Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to <i>t</i>-butylhydroperoxide

A. L. Nieminen, Alice K. Saylor, Samuel A. Tesfai et al. · Biochemical Journal · 1995 · 381 citations · Full text

, , +17