Balanitis due to fixed drug eruption associated with tetracycline therapy.

Abstract

An eruption is called 'fixed' if it recurs at the same site after re-exposure to the drug which precipitated the previous lesion. The eruption is commonly erythematous and sharply defined but may be bullous, herpetiform, or urticarial, and can be solitary or widely scattered. The commonest target areas are the trunk and the proximal portions of the limbs and the mouth, eyes, and urethra may sometimes be involved. Many drugs have been implicated, including phenolphthalein, phenacetin, salicylates, barbiturates, dap- sone, sulphonamides, and tetracycline (Peck and Feldman, 1950; Welsh, 1955; Browne, 1964; Baer and Harris, 1967).