Concepedia

A site–directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination

Andrew J.H. Smith, Maria de Sousa, Bernard Kwabi‐Addo, Amanda Heppell-Parton, Helen Impey, Pamela Rabbitts

Nature Genetics · 1995 · 256 citations · 34 references

DOI

Concepts

References

34

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

Kirk R. Thomas, Mario R. Capecchi · Cell · 1987 · 2.4K citations

, , +9

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

, , +12

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

Victor L. J. Tybulewicz, C. Crawford, Peter K. Jackson et al. · Cell · 1991 · 1.3K citations

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HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper, Kate Hardy, Alan H. Handyside et al. · Nature · 1987 · 1.2K citations

, , +13