Failure of aspirin at different doses to modify experimental thrombosis in rats

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Thrombopoiesis, Thrombosis, Biochemistry +12

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

J. Bryan Smith, A.L. Willis · Nature New Biology · 1971 · 1.5K citations

Inflammation, Thrombosis, Thrombopoiesis +8

Acetylation of prostaglandin synthase by aspirin.

G J Roth, N Stanford, Philip W. Majerus · Proceedings of the National Academy of Sciences · 1975 · 1K citations · Full text

Oocyte, Molecular Pharmacology, Acetyl Salicylic Acid +13

Platelets: A Multidisciplinary Approach

Carel J. van Oss · Immunological Communications · 1979 · 257 citations

Thrombopoiesis, Thrombosis, Engineering +9

Formation of an Intermediate in Prostaglandin Biosynthesis and Its Association with the Platelet Release Reaction

J. Bryan Smith, Carol M. Ingerman, James J. Kocsis et al. · Journal of Clinical Investigation · 1974 · 201 citations · Full text

Platelet Aggregation, Inflammation, Thrombosis +16