Concepedia

Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification

Gregory P. Kalemkerian, Xiaolan Ou, Mohammed R. Adil, Rita Rosati, M. Monir Khoulani, S. Madan, George R. Pettit

Cancer Chemotherapy and Pharmacology · 1999 · 80 citations · 14 references

DOI

Concepts

References

14

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

David L. Vaux, Suzanne Cory, Jerry M. Adams · Nature · 1988 · 3.2K citations

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Inactivation of Bcl-2 by phosphorylation.

Subrata Haldar, Nilamani Jena, C M Croce · Proceedings of the National Academy of Sciences · 1995 · 740 citations

, , +17

Taxol induces bcl-2 phosphorylation and death of prostate cancer cells.

Subrata Haldar, Janaki Chintapalli, C M Croce · PubMed · 1996 · 662 citations

, , +13

The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10

George R. Pettit, Yoshiaki Kamano, Cherry L. Herald et al. · Journal of the American Chemical Society · 1987 · 577 citations

, , +10

Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death.

Mikhail V. Blagosklonny, Paraskevi Giannakakou, Wafik S. El‐Deiry et al. · PubMed · 1997 · 386 citations

, , +17