Concepedia

Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients

Young Wang, Francis P. Kuhajda, Ji Nong Li, Ellen S. Pizer, Wan Fang Han, Lori J. Sokoll, Daniel W. Chan

Cancer Letters · 2001 · 114 citations · 17 references

DOI

Concepts

References

17

Fatty acid synthesis: a potential selective target for antineoplastic therapy.

Francis P. Kuhajda, K Jenner, F D Wood et al. · Proceedings of the National Academy of Sciences · 1994 · 703 citations

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Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts.

Ellen S. Pizer, Jagan N. Thupari, Wan Fang Han et al. · PubMed · 2000 · 369 citations

, , +17

Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma.

L Z Milgraum, Lee A. Witters, Gary R. Pasternack et al. · PubMed · 1997 · 333 citations

, , +16

Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients

Piero Alò, Paolo Visca, Adele Marci et al. · Cancer · 1996 · 319 citations · Full text

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Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival

Ted Gansler, William J. Hardman, Dirk A Hunt et al. · Human Pathology · 1997 · 289 citations

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